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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DES
All Species:
25.15
Human Site:
T149
Identified Species:
69.17
UniProt:
P17661
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P17661
NP_001918.3
470
53536
T149
R
L
K
G
R
E
P
T
R
V
A
E
L
Y
E
Chimpanzee
Pan troglodytes
Q5R1W8
466
53634
S144
Q
L
K
G
Q
G
K
S
R
L
G
D
L
Y
E
Rhesus Macaque
Macaca mulatta
XP_001103922
450
51674
E159
Q
R
A
R
V
D
V
E
R
D
N
L
L
D
D
Dog
Lupus familis
XP_535175
466
53579
S144
Q
L
K
G
Q
G
K
S
R
L
G
D
L
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
P31001
469
53479
T148
R
L
K
G
R
E
P
T
R
V
A
E
L
Y
E
Rat
Rattus norvegicus
P48675
469
53438
T148
R
L
K
G
R
E
P
T
R
V
A
E
L
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02542
463
53261
T140
R
L
R
G
K
Q
P
T
R
V
A
E
M
Y
E
Frog
Xenopus laevis
P23239
458
52783
T137
R
L
K
G
K
E
P
T
R
V
N
E
L
Y
E
Zebra Danio
Brachydanio rerio
Q58EE9
444
51231
E150
N
A
G
K
A
R
L
E
I
E
R
D
N
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.6
95.3
60
N.A.
97.4
97.8
N.A.
N.A.
85.9
80.8
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77.2
95.5
77.2
N.A.
99.1
98.9
N.A.
N.A.
92.5
90.4
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
13.3
46.6
N.A.
100
100
N.A.
N.A.
73.3
86.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
33.3
80
N.A.
100
100
N.A.
N.A.
100
93.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
12
0
0
0
0
0
45
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
12
0
34
0
12
12
% D
% Glu:
0
0
0
0
0
45
0
23
0
12
0
56
0
0
78
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
78
0
23
0
0
0
0
23
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
67
12
23
0
23
0
0
0
0
0
0
0
0
% K
% Leu:
0
78
0
0
0
0
12
0
0
23
0
12
78
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
23
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
56
0
0
0
0
0
0
0
0
% P
% Gln:
34
0
0
0
23
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
56
12
12
12
34
12
0
0
89
0
12
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
12
0
0
56
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
78
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _